The Klondike Gold Rush An estimated 100,000 prospectors made their way to the Klondike region of the Yukon in north-western Canada between 1896 and 1899. The conditions were brutally harsh; frostbite, lost fingers and toes, and death. But there was a big payoff, for some. What has this to do with my books: absolutely nothing. But it has everything to do with... well, let's just keep that in the bag, for now.